The clinical course of HFRS may be divided into five phases on the basis of the underlying physiologic aberrations : febrile, hypotensive, oliguric, diuretic, and convcalescent. But there is a considerable variation among patients in the severity
of the
illness, and generally, HFRS has a benign course though fatal cases and severe complictions have been reported such as panhypopituitarism. We experienced a casers of panhypopituitarism with central diabetes insipidus on convalescent phase of
HFRS.
This
61-year female patient was diagnsoed SFRS by history, clinicla symptoms, and serologic titer to Hantaan virus. On progression, She complained weakness, polyuria above 5L per day, and polydypsia. We examined the level of pituitary hormsons and
water
deprivation test. Those results suggested panhypopituitarism and central diabetes insipidus. After hormone replacement, she felt well and discharged. And now, we report the case with review.
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